Key points
U.S. virologic surveillance
Clinical Laboratories
The results of tests performed by clinical laboratories nationwide are summarized below. Data from clinical laboratories (the percentage of specimens tested that are positive for influenza) are used to monitor whether influenza activity is increasing or decreasing. Nationally, during Week 23, the percentage of respiratory specimens testing positive for influenza virus in clinical laboratories was 1.7%.
| Week 23 | Data Cumulative since September 29, 2024 (Week 40) |
|
|---|---|---|
| No. of specimens tested | 32,752 | 3,513,159 |
| No. of positive specimens (%) | 564 (1.7%) | 486,440 (13.8%) |
| Positive specimens by type | ||
| Influenza A | 198 (35.1%) | 433,160 (89.0%) |
| Influenza B | 366 (64.9%) | 53,280 (11.0%) |
Public Health Laboratories
The results of tests performed by public health laboratories nationwide are summarized below. Data from public health laboratories are used to monitor the proportion of circulating viruses that belong to each influenza virus type/subtype/lineage. Viruses known to be associated with recent live attenuated influenza vaccine (LAIV) receipt or found upon further testing to be a vaccine virus are not included as they are not circulating influenza viruses.
| Week 23 |
Data Cumulative since September 29, 2024 (Week 40) |
|
|---|---|---|
| No. of specimens tested | 495 | 146,540 |
| No. of positive specimens | 60 | 98,208 |
| Positive specimens by type/subtype | ||
| Influenza A | 31 (51.7%) | 92,670 (94.4%) |
| Subtyping Performed | 24 (77.4%) | 83,015 (89.6%) |
| (H1N1)pdm09 | 21 (87.5%) | 43,751 (52.7%) |
| H3N2 | 3 (12.5%) | 39,185 (47.2%) |
| H3N2v | 0 | 0 |
| H5 | 0 | 79 (0.1%) |
| Subtyping not performed | 7 (22.6%) | 9,655 (10.4%) |
| Influenza B | 29 (48.3%) | 5,538 (5.6%) |
| Lineage testing performed | 18 (62.1%) | 3,078 (55.6%) |
| Yamagata lineage | 0 | 0 |
| Victoria lineage | 18 (100%) | 3,078 (100%) |
| Lineage not performed | 11 (37.9%) | 2,460 (44.4%) |
Novel Influenza A Virus Infections
No confirmed human infections with influenza A(H5) virus were reported to ÐÇ¿ÕÓéÀÖ¹ÙÍø this week. To date, human-to-human transmission of avian influenza A(H5) virus (H5 bird flu) has not been identified in the United States.
The CSTE position statement, which includes updated case definitions for confirmed, probable, and suspected cases is available at
An up-to-date human case summary during the current outbreak by state and exposure source is available at www.cdc.gov/bird-flu/situation-summary/index.html
Information about avian influenza is available at /flu/avianflu/index.htm.
A(H5N1) virus interim recommendations for Prevention, Monitoring, and Public Health Investigations are available at /bird-flu/prevention/hpai-interim-recommendations.html.
The latest case reports on avian influenza outbreaks in wild birds, commercial poultry, backyard or hobbyist flocks, and mammals in the United States are available from the USDA at .
Outpatient and Emergency Department Illness Surveillance
Outpatient respiratory illness visits
The U.S. Outpatient Influenza-like Illness Surveillance Network (ILINet) monitors outpatient visits for respiratory illness referred to as influenza-like illness [ILI (fever plus cough or sore throat)], not laboratory-confirmed influenza, and may capture respiratory illness visits due to infection with any pathogen that can present with similar symptoms, including influenza, SARS-CoV-2, and RSV. Therefore, it is important to evaluate syndromic surveillance data, including that from ILINet, in the context of other sources of surveillance data to obtain a complete and accurate picture of influenza, SARS-CoV-2, and other respiratory virus activity.
Nationwide during Week 23, 1.6% of patient visits reported through ILINet were due to respiratory illness that included fever plus a cough or sore throat, also referred to as ILI. Multiple respiratory viruses are co-circulating, and the relative contribution of influenza virus infection to ILI varies by location.
Outpatient respiratory illness visits by age group
More than 70% of ILINet participants provide both the number of patient visits for respiratory illness and the total number of patient visits for the week broken out by age group. Data from this subset of providers are used to calculate the percentages of patient visits for respiratory illness by age group.
During Week 23, the percentage of visits for respiratory illness reported in ILINet was 5.4% among those 0-4 years, 2.2% among those 5-24 years, 1.3% among those 25-49 years, 0.9% among those 50-64 years, and 0.7% among those 65 years and older.
Outpatient respiratory illness activity map
Data collected in ILINet are used to produce a measure of ILI activity* by state/jurisdiction and Core Based Statistical Areas (CBSA).
| Activity Level | Number of Jurisdictions | Number of CBSAs | ||
|---|---|---|---|---|
| Week 23 (Week ending Jun. 7, 2025) |
Week 22 (Week ending May 31, 2025) |
Week 23 (Week ending Jun. 7, 2025) |
Week 22 (Week ending May 31, 2025) |
|
| Very High | 0 | 0 | 0 | 0 |
| High | 0 | 0 | 0 | 1 |
| Moderate | 0 | 0 | 2 | 2 |
| Low | 0 | 2 | 6 | 17 |
| Minimal | 53 | 53 | 666 | 674 |
| Insufficient Data | 2 | 0 | 255 | 235 |
*Data collected in ILINet may disproportionally represent certain populations within a jurisdiction or CBSA, and therefore, may not accurately depict the full picture of influenza activity for the entire jurisdiction or CBSA. Differences in the data presented here by ÐÇ¿ÕÓéÀÖ¹ÙÍø and independently by some health departments likely represent differing levels of data completeness with data presented by the health department likely being the more complete.
National Syndromic Surveillance System (NSSP)
The overall percentage of emergency department (ED) visits with a discharge diagnosis of influenza reported in NSSP was 0.2% during Week 23. The percentage of visits was 0.5% among those 0-4 years, 0.5% among those 5-17 years, 0.2% among those 18-64 years, and 0.1% among those 65 years and older.
Hospitalization surveillance
FluSurv-Net
The Influenza Hospitalization Surveillance Network (FluSurv-NET) conducts population-based surveillance for laboratory-confirmed influenza-related hospitalizations in select counties in 14 states and represents approximately 9% of the U.S. population. FluSurv-NET hospitalization data are preliminary. Patients admitted for laboratory-confirmed influenza-related hospitalization after April 30, 2025, will not be included in FluSurv-NET for the 2024-2025 season. Data on patients admitted through April 30, 2025, will continue to be updated on FluView Interactive as additional information is received.
National Healthcare Safety Network (NHSN) Hospital Respiratory Data
Hospitals report to NHSN the weekly number of patients with laboratory-confirmed influenza who were admitted to the hospital. Nationally, during Week 23, 1,455 (0.4 per 100,000 population) laboratory-confirmed influenza-associated hospitalizations were reported. When examining rates by age, the highest hospital admission rate per 100,000 population was among those 65 years and older (1.2), followed by those 0-4 years (0.5), and the 50-64 years age group (0.4).
Mortality surveillance
National Center for Health Statistics (NCHS) Mortality Surveillance
Based on NCHS mortality surveillance data available on June 12, 2025, 0.1% of the deaths that occurred during the week ending June 7, 2025 (Week 23) were due to influenza. The data presented are preliminary and may change as more data are received and processed.
Influenza-Associated Pediatric Mortality
Five influenza-associated pediatric deaths occurring during the 2024-2025 season were reported to ÐÇ¿ÕÓéÀÖ¹ÙÍø during Week 23. The deaths occurred between weeks 5 and 17 (the weeks ending February 1, 2025, and April 26, 2025, respectively). A total of 246 influenza-associated pediatric deaths occurring during the 2024-2025 season have been reported to ÐÇ¿ÕÓéÀÖ¹ÙÍø. This is the highest number of pediatric deaths reported in any non-pandemic influenza season since the condition became reportable in 2004.
Among children who were eligible for influenza vaccination and with known vaccine status, 90% of reported pediatric deaths this season (compared to 82% during the 2023-2024 season) have occurred in children who were not fully vaccinated against influenza.
Additional National and International Influenza Surveillance Information
Additional surveillance information
FluView Interactive: FluView includes enhanced web-based interactive applications that can provide dynamic visuals of the influenza data collected and analyzed by ÐÇ¿ÕÓéÀÖ¹ÙÍø. These FluView Interactive applications allow people to create customized, visual interpretations of influenza data, as well as make comparisons across flu seasons, regions, age groups and a variety of other demographics.
National Institute for Occupational Safety and Health: Monthly surveillance data on the prevalence of health-related workplace absenteeism among full-time workers in the United States are available from NIOSH.
U.S. State and local influenza surveillance: Select a jurisdiction below to access the latest local influenza information.
Public Health Agency of Canada:
The most up-to-date influenza information from Canada is available in .
Public Health England:
The most up-to-date influenza information from the United Kingdom is available from .
Any links provided to non-Federal organizations are provided solely as a service to our users. These links do not constitute an endorsement of these organizations or their programs by ÐÇ¿ÕÓéÀÖ¹ÙÍø or the Federal Government, and none should be inferred. ÐÇ¿ÕÓéÀÖ¹ÙÍø is not responsible for the content of the individual organization web pages found at these links.
A description of the ÐÇ¿ÕÓéÀÖ¹ÙÍø influenza surveillance system, including methodology and detailed descriptions of each data component is available on the page.