At a glance
Undetectable = Untransmittable (U=U) is an essential strategy for HIV prevention and a community-led global health campaign. ÐÇ¿ÕÓéÀÖ¹ÙÍø is a leader in the global movement to promote U=U and ultimately prevent HIV transmission.

Overview
Sustained antiretroviral treatment (ART) reduces the amount of HIV in the body to undetectable levels in viral load tests. Studies have demonstrated that people living with HIV with an undetectable viral load cannot transmit HIV to sexual partners. This science, or treatment as prevention (TasP), is one of the most effective biomedical tools for preventing HIV transmission.
U=U (Undetectable = Untransmittable), launched in 2016 by the , is a community-led global health and human rights movement with over 1,000 official partners in 105 countries. U=U simplifies the science to the lifesaving message: A person living with HIV who is on treatment and maintains an undetectable viral load has zero risk of transmitting HIV to their sexual partners.
Implementing and scaling up U=U
ÐÇ¿ÕÓéÀÖ¹ÙÍø is a key implementer of the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR). ÐÇ¿ÕÓéÀÖ¹ÙÍø uses innovation and data-driven approaches to help eliminate HIV as a global public health threat, sustaining and accelerating PEPFAR's lifesaving achievements of more than twenty years.
In partnership with PAC, ÐÇ¿ÕÓéÀÖ¹ÙÍø developed the “Implementing and Scaling Up Undetectable = Untransmittable (U=U)” resource guide, to help partners implement and champion U=U in PEPFAR-supported countries and beyond.
This guide can help public health officials, healthcare professionals, and advocates understand U=U, place it in a scientific context, and communicate it effectively as a public health intervention. It can also help partners to create a strategic plan, implement activities, and monitor and evaluate progress, with resources and examples for support.
The lifesaving message of U=U
Watch ÐÇ¿ÕÓéÀÖ¹ÙÍø expert Monique Carry, Ph.D., MA, discuss the importance of U=U with Miguel Gomez, Director, and Deondre Moore, from the (PACHA), and Jesse Milan, Jr., JD, a member of PACHA, and the PEPFAR Scientific Advisory Committee, at the 25th International AIDS Conference.
Supporting global strategies to end HIV

Beyond improving adherence to treatment, U=U supports the achievement of the .
As an individual-level intervention, U=U can:
- Increase the uptake of HIV testing services
- Improve treatment adherence and viral suppression
- Improve the quality of life and well-being of people living with HIV
As a community and organizational-level intervention, U=U can:
- Improve understanding of the benefits of HIV treatment
- Champion access to care and treatment
- Reduce HIV-related stigma and discrimination