Notice to Readers
Unavailability of Streptomycin and Para-Aminosalicylic Acid
in the United States
Streptomycin (SM) and para-aminosalicylic acid (PAS),
antimicrobial agents used to treat tuberculosis (TB), are currently
unavailable in the United States. Because of problems in the supply
of bulk SM, which is produced outside the United States, the U.S.
manufacturer has ceased production of the finished product. The
U.S. manufacturer of PAS has voluntarily discontinued production on
a temporary basis. Although ÐÇ¿ÕÓéÀÖ¹ÙÍø and the Food and Drug
Administration are attempting to reestablish production of these
drugs, health-care providers should be prepared for an interruption
in their supply. For guidance in selecting appropriate alternatives
to SM and PAS for the treatment of TB, health-care providers should
contact their state or local TB control program.
Disclaimer
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