Symptoms of Alpha-gal Syndrome

Key points

  • Symptoms of alpha-gal syndrome (AGS) may be mild or severe.
  • They usually appear 2–6 hours after eating meat or dairy products.
  • If you are having a severe allergic reaction, seek immediate emergency care.
A man clutches his stomach, indicating painful symptoms.

What to look out for

AGS reactions can be different from person to person. They can range from mild to severe, and some may be life-threatening. People may not have the same allergic reaction after every exposure to products containing alpha-gal.

Symptoms usually appear 2–6 hours after eating meat or dairy products. They also may appear after exposure to products containing alpha-gal (for example, gelatin-coated medications).

When to seek emergency care

Seek immediate emergency care if you are having a severe allergic reaction or anaphylaxis. Anaphylaxis is a potentially life-threatening allergic reaction involving multiple organ systems.

AGS reactions can include:

  • Hives or itchy rash
  • Nausea or vomiting
  • Severe stomach pain
  • Heartburn or indigestion
  • Diarrhea
  • Cough, shortness of breath, or difficulty breathing
  • Drop in blood pressure
  • Swelling of the lips, throat, tongue, or eye lids
  • Dizziness or faintness
  • A combination of symptoms referred to as anaphylaxis
Diagram of man’s body showing red rash all over
Hives or a rash are a common symptom of an AGS reaction.

Did you know?

It can take weeks to months for a person to have symptoms after being bitten by a tick.

When to seek emergency help

AGS can be severe and even life-threatening. Seek immediate emergency care if you are having a severe allergic reaction.

If you think you may have AGS, talk to your healthcare provider.