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Overview

ÐÇ¿ÕÓéÀÖ¹ÙÍø maintains 24/7 capability to quickly find and help people at risk of contact with harmful chemicals during a public health emergency. Chemical threat agents can be poisonous vapors, aerosols, liquids, or solids that have toxic effects on people. These chemicals can be naturally occurring in the environment or synthetically produced. Chemical releases can be unintentional, as in the case of an industrial accident, or intentional, as in the case of a terrorist attack. Early detection and accurate identification are critical to enable effective treatment and to prevent additional exposures of chemical threats.

Projects and initiatives

Detecting new and likely threats

ÐÇ¿ÕÓéÀÖ¹ÙÍø develops and performs unique laboratory tests, such as the Rapid Toxic Screen, that assess urine and blood to identify chemical exposures in people during a public health emergency or terrorist event. The Rapid Toxic Screen (RTS) is a series of tests that can detect up to 150 chemical agents in 40 samples within 36 hours of receipt at ÐÇ¿ÕÓéÀÖ¹ÙÍø. After identifying the chemicals causing problems, ÐÇ¿ÕÓéÀÖ¹ÙÍø can measure up to 1,000 patient samples per day during an emergency. Results of the Rapid Toxic Screen help identify which chemicals were used, who was exposed to the chemicals, and how much of a particular chemical their bodies absorbed. This information is critical to medical and public health personnel managing a chemical public health emergency.

ÐÇ¿ÕÓéÀÖ¹ÙÍø maintains 24-7 laboratory response capability and can deploy the Chemical Emergency Response Team within two hours of a request to assist with specimen collection, packaging, storage, and shipment. ÐÇ¿ÕÓéÀÖ¹ÙÍø scientists work with state and local officials to collect samples and transport them to ÐÇ¿ÕÓéÀÖ¹ÙÍø where testing can be done to assess people's exposure to chemical agents.

In addition, ÐÇ¿ÕÓéÀÖ¹ÙÍø works with public health laboratories in states, territories, cities, and counties through the Laboratory Response Network – Chemical (LRN-C) to assist in expanding local laboratory capacity and preparedness for response to chemical threats.

Response to toxins

ÐÇ¿ÕÓéÀÖ¹ÙÍø develops unique, mass spectrometry-based methods to rapidly and accurately detect and diagnose diseases from dangerous toxins and living things that make toxins. ÐÇ¿ÕÓéÀÖ¹ÙÍø has developed specific and sensitive methods for toxins from bacteria, fungi, and algae.

Improving laboratory detection of synthetic opioids in the U.S.

Laboratories have a key role in the response to the opioid overdose epidemic. Successful detection and identification of opioids and other drugs mixed with opioids in clinical, research, and environmental samples largely depend on a testing laboratory's access to reference standards for confirmation.