Hepatitis B Surveillance 2021

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What Is Hepatitis B

Hepatitis B is a vaccine-preventable liver disease caused by the hepatitis B virus (HBV). HBV is transmitted when blood, semen, or another body fluid from a person infected with the virus enters the body of someone who is uninfected.

This can happen through sexual contact; sharing needles, syringes, or other drug-injection equipment; or from the gestational parent to baby during pregnancy or at birth.

For some persons, hepatitis B is an acute, or short-term, illness; for others, it can become a long-term, chronic infection. Chronic hepatitis B can lead to serious health problems, including cirrhosis, liver cancer, and death.

Treatments are available, but no cure exists for hepatitis B. The best way to prevent hepatitis B is by being vaccinated.

Hepatitis B in 2021

Acute Hepatitis B

2,045

There were 2,045 new cases of acute hepatitis B reported during 2021

13,300

There were 13,300 estimated acute hepatitis B virus infections during 2021

Chronic Hepatitis B

14,229

There were 14,229 cases of newly reported chronic hepatitis B during 2021

5.9

There were 5.9 newly reported cases of chronic hepatitis B per 100,000 people during 2021

Acute Hepatitis B

During 2021, 47 states reported 2,045 acute hepatitis B cases resulting in an estimated 13,300 infections. After a decade of stable rates, the rate of acute hepatitis B abruptly decreased in 2020; the rate decreased again by 14% in 2021. This decrease may be related to fewer people seeking healthcare and being tested for hepatitis B during the COVID-19 pandemic.

Hepatitis B Prevention

Hepatitis B vaccination prevents hepatitis B. Reported cases of acute hepatitis B decreased after ÐÇ¿ÕÓéÀÖ¹ÙÍø recommended routine child vaccination in 1991. The decrease continued until 2011, leveled off, and then declined again in 2020 and 2021, which may be due to the COVID-19 pandemic.

To further decrease hepatitis B incidence, ÐÇ¿ÕÓéÀÖ¹ÙÍø published the 2022 universal hepatitis B adult vaccination recommendation calling for all people aged 19–59 years to receive hepatitis B vaccine whether they have risk factors or not.

Fast Facts About Acute Hepatitis B in 2021

14%

The rate of reported acute hepatitis B cases decreased 14% from 2020–2021

73%

73% of all acute hepatitis B cases were persons aged 30–59 years

Appalachian region

States in the Appalachian region had rates of acute hepatitis B higher than the US average

Non-Hispanic Black

Rates of acute hepatitis B were highest among non-Hispanic Black persons

Chronic Hepatitis B

During 2021, a total of 14,229 newly reported cases of chronic hepatitis B, corresponding to a rate of 5.9 cases per 100,000 people.

The rate of newly reported chronic hepatitis B cases among non-Hispanic Asian/Pacific Islander persons (27.0 cases per 100,000 people) was 14 times the rate among non-Hispanic White persons (1.9 cases per 100,000 people).

Fast Facts About Chronic Hepatitis B in 2021

In 2021, the rate of newly reported chronic hepatitis B was 14x higher among non-Hispanic Asian/Pacific Islander persons than among non-Hispanic White persons

89% of newly reported chronic hepatitis B cases occurred in persons 30 years and older

Although the rate of reported acute hepatitis B was the lowest among non-Hispanic Asian/Pacific Islander persons, the rate of newly reported chronic hepatitis B was highest among this group
Hepatitis B Figures and Tables